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High-Protein Spinach and Artichoke Chicken Casserole

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This High-Protein Spinach and Artichoke Chicken Casserole is the perfect balance of delicious and nutritious. Packed with tender chicken, fresh spinach, creamy artichoke, and a cheesy topping, it’s a hearty, low-carb dish that’s perfect for anyone looking to boost their protein intake. Enjoy this comforting casserole with the whole family or meal prep for the week! 

Ingredients

Scale
  • 4 boneless, skinless chicken breasts (cooked and shredded)
  • 1 can (14 oz) artichoke hearts, drained and chopped
  • 3 cups fresh spinach (chopped)
  • 1/2 cup plain Greek yogurt
  • 1/2 cup mayonnaise
  • 1 cup shredded mozzarella cheese
  • 1/2 cup grated Parmesan cheese
  • 1 teaspoon garlic powder
  • 1 teaspoon onion powder
  • Salt and pepper to taste
  • 1 tablespoon olive oil (for sautéing spinach)
  • 1/2 teaspoon red pepper flakes (optional, for extra flavor)
  • Fresh parsley for garnish (optional)

Instructions

  • Prepare the chicken: Cook the chicken breasts (grilled, baked, or boiled) until fully cooked, then shred using two forks. Set aside.
  • Sauté the spinach: In a large skillet, heat the olive oil over medium heat. Add the chopped spinach and sauté for 3-4 minutes until wilted. Remove from heat and set aside to cool slightly.
  • Mix the casserole base: In a large mixing bowl, combine the shredded chicken, sautéed spinach, chopped artichokes, Greek yogurt, mayonnaise, mozzarella cheese, Parmesan cheese, garlic powder, onion powder, salt, pepper, and red pepper flakes (if using). Stir until well combined.
  • Assemble the casserole: Preheat the oven to 375°F (190°C). Transfer the mixture into a greased 9×13-inch baking dish, spreading it evenly.
  • Bake: Bake for 20-25 minutes, or until the top is golden brown and the casserole is heated through.
  • Serve: Remove from the oven and let it cool for a few minutes. Garnish with fresh parsley if desired. Serve hot and enjoy!

Notes

  • You can use rotisserie chicken for a quicker option.
  • For a dairy-free version, substitute Greek yogurt and cheese with plant-based alternatives.
  • This casserole is perfect for meal prep and can be stored in the refrigerator for up to 4 days.
  • For added texture, you can sprinkle some breadcrumbs on top before baking.

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